The science of
SKIN LONGEVITY

With real science driving skin longevity

The INÜO era begins

Every day, the skin faces invisible threats—both internal and external—that challenge its natural ability to repair and regenerate.

Anticipating damage, strengthening innate defenses, and enhancing the skin’s regenerative capacity is undoubtedly a powerful strategy.

Going deep into the skin and strengthening its own defense mechanisms is THE EXCITING INÜO REVOLUTION.

HIGH - performance
TECHNOLOGY
+ ADVANCED
COSMETICS

INÜO is the first dermofacial system that addresses the structural challenges of skin aging in a coordinated, science-based way, combining high-performance cosmetics with intelligent technologies in a unified protocol.

PROTECTS

Strengthening the skin barrier, microbiome and immune balance

BLOCKS

Glycation and oxidative degradation

REPAIRS

Reactivating the skin’s regenerative signals

A multilayer treatment strategy that:

It's not just about care...

It is a new treatment strategy that builds long-term skin resilience, from prevention to deep structural repair.

It’s not just about care…

It is a new treatment strategy that builds long-term skin resilience, from prevention to deep structural repair.

A COHERENT DESIGN

DERMOFACIAL TECHNOLOGIES

Each step of the protocol is designed to unlock the skin’s maximum potential, layer by layer, from the deepest levels to the surface. A precise, non-redundant sequence that cleanses, repairs, protects, and builds long-term resilience.

Step_1

drains
Activates
Decongests

Step_2

cleans Exfoliates Oxygenates

Step_3

Infusies Nourishes Hydrates

Step_4

Integrates Stimulates Builds

Step_5

Regenerates Protects Soothes

[01]

Drains · Decongests · balances

Massage

A step as simple as it is essential: activating facial lymphatic and circulatory flow.MASSAGE, through a delicate rotational massage, promotes the elimination of toxins, reduces facial congestion, and restores skin vitality, amplifying treatment results and improving the integration of cosmetic actives.A functional gesture with a significant physiological and sensorial impact.

[02]

Cleans· exfoliates · oxygenates

O₂XY

Frees the skin from impurities.

O₂XY gently exfoliates the skin, removing contaminants, excess oil, and debris, while enhancing tissue oxygenation.

A gentle vibration and ergonomic design ensure a delicate and precise application throughout the entire treatment.

the power of oxygenation

O₂XY combines microvibration with INÜO’s exclusive capsule to activate the Bohr effect. The skin releases more oxygen exactly where it is needed—without external infusion.More cellular energy, revitalized skin, and enhanced readiness to absorb active ingredients from the very first step.

[03]

infuses· NOURISHES · HYDRATES

NFUSE

Precision and controlHigh-precision infusion/suction technology that allows total control of flow and vacuum for targeted application of cosmetic serums.Disposable diamond tips perform a very gentle, even exfoliation, preparing the skin without altering its natural barrier.NFUSE ensures comfort and control throughout the treatment, delivering consistent results while minimizing product waste

MOLECULAR DEFENSE STRATEGY

NFUSE performs a very gentle exfoliation that temporarily relaxes the bonds between corneocytes, improving permeability and the absorption of INÜO cosmetic formulas, enriched with selected active ingredients.The combination NFUSE + Üceuticals constitutes the strategic core of a treatment that nourishes, stimulates, hydrates, and protects the skin, adapting to its specific needs.

[04]

integra · estimula · construye

ULTRAPULSE

ENHANCED INFUSION

This high-frequency, athermal ultrasound technology temporarily increases skin permeability without altering its natural barrier, facilitating the penetration of the applied cosmetic actives.

HYALMAX

TARGETED STIMULATION OF DERMAL RENEWAL

Uses pulsed ultrasound to reactivate senescent fibroblasts, stimulating the synthesis of collagen, elastin, and glycosaminoglycans (GAGs), essential components of the extracellular matrix (ECM) responsible for hydration, firmness, and the skin’s structural integrity.

DOUBLE STIMULATION

This dual stimulation reinforces the skin’s architecture and improves elasticity, restoring volume and flexibility. Well-hydrated, metabolically active skin is naturally more resilient to oxidative stress, glycation, and external aggressors.ULTRAPULSE + HYALMAX strengthen the skin’s regenerative core, building long-lasting defense from within.

[05]

REGENERATES· PROTECTS · CALMS

CHROMIX

LED Photobiomodulation Technology Activates cellular receptors and stimulates key regenerative pathways, adapting to each skin’s unique needs through specific wavelength ranges:

INFRARED LIGHT (IR)

With anti-inflammatory and immunomodulatory effects. Calms the skin and regulates immune responses, reducing silent inflammation and restoring intercellular communication between layers.

BLUE LIGHT

Balances the skin microbiota. Controls and inactivates acne-related bacteria, helping to keep the skin clear and stable.

RED LIGHT

Acts in depth, stimulating collagen production and optimizing cellular metabolism.

CHROMIX enhances natural repair mechanisms and prolongs the benefits of the entire INÜO protocol.A final gesture that delivers light, balance, and regeneration down to the deepest layers of the skin.

INTEGRATED
FUNCTIONAL COSMETICS

A functional resilience strategy

Üceuticals is a cosmetic line born with a clear biological mission: to protect the skin from the nucleus outward and build resilience.Each formula has been designed to combat glycation, oxidation, and deterioration of the skin barrier, while promoting microbiome balance—the skin’s first line of biological intelligence.

ZERO PEEL

Gentle, high-tolerance epidermal renewal

A peel formulated to promote progressive, controlled exfoliation in sensitive, reactive, or barrier-compromised skin.

ZERO PEEL promotes controlled renewal that enhances skin quality while maintaining epidermal integrity and comfort, even in highly sensitive skin.

OXYGENATING PEEL

ÜPOD + Ü Activating Gel

Soothing and barrier reinforcement.

The combination of ÜPOD + Ü Activating Gel creates a controlled effervescence that activates and oxygenates the skin.Its exfoliating action removes impurities and residue, leaving the skin clean and optimally prepared for active absorption.

Biological action
Enhances surface renewal Stimulates tissue oxygenation Optimizes skin permeability Activates the skin’s metabolic response

Oxygenating Peel is indicated for normal, combination, or resilient skin that can tolerate a higher level of stimulation within Step 1 of the INÜO protocol.

TRIOME+™

Skin balance and longevity

A cosmetic complex that combines antioxidant and anti-glycation action with support for the skin ecosystem and stimulation of the skin’s natural renewal processes.TRIOME+™ helps prevent damage, protect structural integrity, and activate regeneration. It acts across the key biological pathways of skin aging.

Ceramide reload

Epidermal restructuring for barrier-compromised skin

A serum formulated with lipid actives, osmoprotectants, and microbiome-modulating ingredients to support the progressive and long-lasting recovery of moisture balance and barrier function.

AGE Strategy

An elixir for mature and photoaged skin

Designed for skin experiencing loss of density, AGE STRATEGY supports regeneration, cellular energy, and overall skin balance.Its formula combines antioxidant protection, cellular activation, and structural support to help achieve firmer, denser, and visibly rejuvenated skin.

LIGHT UP

Cellular energy and early-age prevention

A serum formulated to help maintain skin vitality in younger to mid-age skin, addressing the early signs of aging.Light Up supports cellular activation, reinforces antioxidant protection, and enhances intercellular communication, helping maintain long-term skin balance.

CLEAR RESET

Balance for oily skin

A serum formulated to help rebalance skin with excess sebum, enlarged pores, or exposure to environmental pollution. It promotes a clearer, more even complexion while helping restore the skin’s natural balance.Its combination of gentle antimicrobial actives, sebum regulators, and mild exfoliants helps progressively improve skin quality without compromising comfort.

REVITALIZING BIOMASK

Soothing and barrier reinforcement

A mask formulated to restore skin balance following the activation and treatment phase. Revitalizing Biomask works to reinforce epidermal eubiosis and consolidate the integrity of the skin barrier.

Its action supports physiological recovery, optimizes hydration, and prolongs the benefits achieved in the previous steps of the protocol.

By reinforcing the microbiota and restoring homeostasis, it promotes more balanced, resilient skin, functionally prepared to sustain long-term results.

The INÜO effects

PHYSIOLOGY

The multilayer approach of INÜO for skin protection and repair goes beyond expectations. Our strategy addresses the full structural complexity of the skin, intervening at every level where damage begins, enhancing regeneration, blocking molecular aggressors, and protecting the integrity of the skin barrier.

[+] At the molecular level, it blocks the progression of glycation and oxidation within dermal structures, preventing the formation of advanced glycation end products (AGEs) and the accumulation of free radicals.

[+] It strengthens the epidermal barrier through biomimetic lipids and ceramides, reducing transepidermal water loss and preventing the infiltration of environmental contaminants.

[+] It modulates the inflammatory response by reducing activation of the inflammasome and restoring skin eubiosis, promoting a more balanced and resilient dermal ecosystem.

[+] It stimulates fibroblasts and supports the skin’s natural regenerative responses, preserving homeostasis and long-term skin integrity.

[+] Functionally, it also promotes lymphatic drainage, helping to reduce swelling and eliminate accumulated metabolic waste.

[+] All of this is achieved through a concept of skin-respectful treatment, which integrates seamlessly into modern clinical practice. INÜO complements and enhances current anti-aging therapies, becoming a key component of a comprehensive, long-term strategy for skin health and longevity.

Revitalizing treatment: Zero Peel + Clear Reset serum. Hyalmax + Ultrapulse. Chromix (IR and red).

The science of SKIN LONGEVITY

HIGH - performance TECHNOLOGY + ADVANCED COSMETICS